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Showing posts with the label Molecular Biochemistry

A Crisis That Rebuilt Me: Lessons from My PhD Journey in Akola

When I moved to Akola to begin my PhD, I genuinely believed survival would be easy. I was wrong. What followed became one of the most mentally demanding phases of my life. To my readers, I apologize for not updating this blog for nearly two years. That silence did not come from comfort or stability—it came from struggle. This period marked a clear crisis point in my PhD journey, both intellectually and personally. Paradoxically, this phase also carried quite a few achievements. Before entering this transition, I had already published four research papers based on my earlier work. During this difficult period, I undertook my first major review article —a task that tested my patience and endurance far more than any experiment. That single review took nearly eleven months to complete. It moved slowly, stalled often, and forced me to read deeply, critically, and repeatedly. At the time, it felt like stagnation. In hindsight, it trained me to think like a scientist rather than merely ex...

Cow’s antibodies could be the newest weapon against COVID-19

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Time for a different type of HERD IMMUNITY!🐄 Last week it was reported that a biopharmaceutical company in the US are using genetically modified cows to produce antibodies that could help us to fight COVID-19. I was intrigued when I saw the headline so had to do some more digging. As coronavirus marches around the globe, a sleepy town on the rugged Maine coast has become an unlikely nucleus in researchers’ efforts to combat the disease, known as COVID-19. The Jackson Laboratory, a is rushing to produce stocks of a transgenic animal that scientists hope will help them to understand the virus. . So what makes cows so special? Cows make good antibody factories, and not just because they have more blood than smaller animals engineered to synthesize human versions of the proteins. Their blood can also contain twice as many antibodies per millilitre as human blood Well, they actually produce a load of antibodies. Because they have more blood than humans but they can also produce twice as ma...

Stereochemistry an Introduction

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Stereochemistry an Introduction I'm made to realise that I'm not clear enough or good at something, I try to make myself clear with it. It happened , I am preparing for my exam during my preparation for Exam , The question was asked about Stereoisomer but, unfortunately, I was not very clear with the molecular reason behind it.(but, still I managed to answer the question as I know the theoretical information from my notes, but, knowing the molecular mechanism behind each concept clearly is very important, isn't it?). But, nothing is wrong in it, I made myself clear with it now. That's good, right? So, let me share with you some basic principle and an introduction with Streochemistry and how it affects molecular structure, Biochemistry and Metabolism so here we go Just like with any other field of science, chemistry is not two dimensional. To get an accurate chemical analysis, the three-dimensional spatial arrangements of the atoms (and ions) in the molec...